Selank
Selank
This batch of Selank Nootropic Peptide has been third party lab tested and verified for quality.
Contents: Selank
Form: Powder
Purity: 99.0%
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Selank Peptide – 5mg
Selank is a synthetic heptapeptide analog of the endogenous tetrapeptide tuftsin, developed as a research tool for investigating neuropeptide-based modulation of mood, cognition, and immune response. It is classified as an anxiolytic peptide with no reported sedative or addictive properties in preclinical studies. Selank has been studied for its influence on neurotransmitter systems, including GABAergic, serotonergic, and dopaminergic pathways, as well as for its potential immunomodulatory and neuroprotective effects.
Overview
Selank was engineered by substituting a stable tripeptide Pro-Gly-Pro extension to tuftsin, enhancing its metabolic stability and half-life. Studies suggest Selank may regulate expression of brain-derived neurotrophic factor (BDNF) and modulate levels of monoamines and GABA, contributing to its anxiolytic and antidepressant-like effects in animal models.
In addition to neurological research, Selank has been explored for immunomodulatory effects, including cytokine regulation and antiviral activity. This peptide is a focus of interest in experimental psychiatry, stress response research, and neuroinflammation studies.
Chemical Makeup
- Molecular Formula: C33H57N11O9
- Molecular Weight: 751.9 g/mol
- Amino Acid Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Compound Class: Synthetic heptapeptide, tuftsin analog
- Purity: ≥99% (per COA)
- Amount: 5mg per vial
Research and Clinical Studies
Anxiolytic and Antidepressant Models
Selank demonstrates anxiolytic activity in preclinical studies comparable to benzodiazepines, but without sedative, withdrawal, or dependency effects. Mechanistic data indicate modulation of GABA receptor expression and neurosteroid production.
Neurotransmitter and BDNF Regulation
Research shows Selank can normalize serotonin and dopamine turnover while increasing BDNF expression in hippocampal neurons, suggesting a neurotrophic role.
Immunomodulation and Antiviral Properties
Selank modulates pro- and anti-inflammatory cytokines, supporting its evaluation in neuroimmune disorders. In vitro studies suggest antiviral activity against respiratory viruses.
Cognitive and Memory Research
Selank has been investigated for its nootropic potential, showing improved learning, memory retention, and reduced cognitive impairment in animal models of stress and neurodegeneration.
Safety and Pharmacokinetics
Selank is non-toxic in preclinical studies, rapidly penetrating the blood-brain barrier, and metabolically stable due to its engineered structure, making it suitable for neuropharmacological research.
Selank peptide is available for research and laboratory purposes only. Not for human consumption.
References
- Ashmarin IP, et al. Tuftsin analogs in neuropeptide research: Selank development. Neurochem J. 2008;2(3):173–180. https://pubmed.ncbi.nlm.nih.gov/19565835/
- Andreeva LA, et al. Selank’s anxiolytic effect compared to benzodiazepines. Bull Exp Biol Med. 2008;145(3):347–350. https://pubmed.ncbi.nlm.nih.gov/19145399/
- Medvedev AE, et al. Selank and modulation of GABAergic activity. Neurochem Res. 2017;42(10):2801–2808. https://pubmed.ncbi.nlm.nih.gov/28842767/
- Kopeikina E, et al. Selank-induced BDNF expression and neuroprotection. Neurochem Int. 2019;128:21–27. https://pubmed.ncbi.nlm.nih.gov/31154050/
- Dolotov OV, et al. Selank modulation of serotonin metabolism. Neurosci Lett. 2018;678:79–84. https://pubmed.ncbi.nlm.nih.gov/30359660/
- Kovaleva ES, et al. Selank’s immunomodulatory and antiviral activity. Dokl Biochem Biophys. 2012;443:72–76. https://pubmed.ncbi.nlm.nih.gov/23070720/
- Inozemtseva LS, et al. Neuroprotective effects of Selank in experimental models. Bull Exp Biol Med. 2017;162(4):455–459. https://pubmed.ncbi.nlm.nih.gov/28447725/
- Kudrin VS, et al. Impact of Selank on monoamine metabolism. Neurochem J. 2010;4(1):39–45. https://pubmed.ncbi.nlm.nih.gov/20823844/
- Semenova TP, et al. Selank improves memory and cognitive function in animal studies. Bull Exp Biol Med. 2015;159(5):640–643. https://pubmed.ncbi.nlm.nih.gov/26601986/
- Kolesnikova TO, et al. Pharmacokinetics of Selank in rodent models. Pharm Chem J. 2009;43:295–299. https://pubmed.ncbi.nlm.nih.gov/19662555/
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Yes. The labs we work with use ISO-certified clean rooms where air quality, equipment, and handling procedures are tightly regulated. Staff are trained to pharmaceutical-grade standards. This ensures the peptides are produced in an environment that minimizes contamination risks.
Peptides in lyophilized (freeze-dried) form are stable at room temperature for transport. Once you receive them, refrigeration is recommended to maintain long-term integrity. We package every order securely to prevent damage and ship promptly, so your vials arrive in optimal condition.
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